Write the name of the platinum complex used in the treatment of cancer.
Answer:
Cisplatin — [PtCl2(NH3)2]
Explanation:
The platinum complex cisplatin (cis-diamminedichloroplatinum(II)) is an anticancer drug used in chemotherapy.
Its structure contains two ammonia and two chloride ligands in a cis configuration around the platinum(II) center: \[ [\text{PtCl}_2(\text{NH}_3)_2] \]
It works by binding to DNA and preventing cell division in cancer cells.
The correct IUPAC name of \([ \text{Pt}(\text{NH}_3)_2\text{Cl}_2 ]^{2+} \) is:
The Crystal Field Theory (CFT) of coordination compounds is based on the effect of different crystal fields (provided by the ligands taken as point charges) on the degeneracy of d-orbital energies of the central metal atom/ion. The splitting of the d-orbitals provides different electronic arrangements in strong and weak crystal fields. In tetrahedral coordination entity formation, the d-orbital splitting is smaller as compared to the octahedral entity.
What is crystal field splitting energy?
The Crystal Field Theory (CFT) of coordination compounds is based on the effect of different crystal fields (provided by the ligands taken as point charges) on the degeneracy of d-orbital energies of the central metal atom/ion. The splitting of the d-orbitals provides different electronic arrangements in strong and weak crystal fields. In tetrahedral coordination entity formation, the d-orbital splitting is smaller as compared to the octahedral entity.
On the basis of CFT, explain why [Ti(H$_2$O)$_6$]Cl$_3$ complex is coloured? What happens on heating the complex [Ti(H$_2$O)$_6$]Cl$_3$? Give reason.