Stem cells can self-renew and differentiate into specialised cell types, which enables several key applications. Regenerative therapy uses stem cells to replace or repair damaged tissues in conditions such as myocardial infarction, spinal cord injury, and neurodegenerative diseases. Haematopoietic stem cell transplants treat blood disorders like leukemia, thalassemia, and severe aplastic anemia by replenishing healthy blood and immune cells. Tissue and organ engineering employs stem cells with scaffolds and growth factors to grow tissues or organoids for transplantation or modelling. Drug testing and research use stem-cell-derived specialised cells to evaluate drug safety and efficacy and to model human diseases in vitro, reducing reliance on animal models.