Microorganisms are harmful in many ways. Some of the microorganisms cause diseases in human beings, plants and animals. Such disease-causing microorganisms are called pathogens. Some microorganisms spoil food, clothing and leather. Some of the common diseases affecting humans are cholera, common cold, chicken pox and tuberculosis. Several microorganisms not only cause diseases in humans but also in animals. For example, anthrax is a dangerous human and cattle disease caused by a bacterium. Disease causing microorganisms in plants like wheat, rice, potato, sugarcane, orange, apple and others reduce the yield of crops.