Question:
Why does a patient of ADA-deficiency require repeated infusions of genetically engineered lymphocytes? Suggest a possible permanent remedy.
Why does a patient of ADA-deficiency require repeated infusions of genetically engineered lymphocytes? Suggest a possible permanent remedy.
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Gene therapy for ADA deficiency is a promising approach for curing immune disorders.
Updated On: Jan 20, 2025
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Solution and Explanation
ADA (Adenosine Deaminase) deficiency leads to severe immune system dysfunction.
Repeated infusions of genetically engineered lymphocytes temporarily restore immune function.
Permanent Remedy: Gene therapy to introduce a functional ADA gene into the patient's bone marrow cells, ensuring lifelong enzyme production.
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