Let's review each of the statements:
A - "High fatality risk to mother" is a possible drawback of IVF, as the procedure may carry risks for the mother.
B - "Expensive instruments and reagents" is also a drawback, as IVF procedures are typically costly due to the need for specialized equipment and medications.
C - "Husband/wife necessary for being donors" is also a limitation, as IVF usually requires genetic material from both partners.
D - "Less adoption of orphans" is true, as IVF procedures may reduce the number of adoptions, since more individuals may choose to have biological children through IVF.
E - "Not available in India" is incorrect, as IVF is available in India.
F - "Possibility that the early embryo does not survive" is also a significant drawback, as embryos may not always implant successfully or survive.
Thus, the correct answer is A, C, D, F only.