Transgenic animals are those that have had a foreign gene deliberately inserted into their genome. They are produced for a variety of scientific, medical, and industrial reasons. Here are four major reasons:
Transgenic animals help scientists understand how specific genes work.
By adding or removing genes, researchers can study their role in development, immunity, diseases, and metabolism.
For example, knockout mice are used to investigate the function of individual genes.
They are used to mimic human genetic disorders, helping researchers study the disease progression and test potential treatments.
Diseases like cystic fibrosis, cancer, Alzheimer’s, and diabetes have been studied using transgenic mice.
Transgenic animals can be engineered to produce human proteins in their milk, eggs, or blood (a process called “gene pharming”).
Example: Transgenic goats producing antithrombin, a protein used to prevent blood clots in humans.
Genes can be inserted to improve traits such as growth rate, disease resistance, milk production, or meat quality.
This helps in creating more productive and disease-resistant animals, enhancing agricultural efficiency.
(a) Write the palindromic nucleotide sequence for following sequence of DNA segment:
5' – GAATTC – 3'
(b) Name the restriction endonuclease that recognizes this sequence.
(c) How are sticky ends produced? Mention their role.