Question

While cementing an all-ceramic bridge, the chair side assistant was accidentally exposed to hydrofluoric etchant. Which of the following should be used as an antidote?

• A. Sodium bicarbonate gel
• B. Potassium hydroxide gel
• C. Calcium hydroxide gel
• D. Calcium gluconate gel

Hint:

Hydrofluoric acid exposure requires immediate treatment with calcium gluconate to neutralize fluoride ions and prevent hypocalcemia.

Answer 1

The Correct Option is D

Step 1: Understanding hydrofluoric acid toxicity.
Hydrofluoric acid (HF) is highly corrosive and dangerousUnlike other acids, it penetrates deep into tissues and binds to calcium and magnesium ions in the bodyThis can cause severe tissue destruction and systemic toxicity
Step 2: Mechanism of damage.
Fluoride ions released from hydrofluoric acid bind to calcium in tissues and bloodThis leads to hypocalcemia, cellular damage, and potentially life-threatening complicationsTherefore, treatment must neutralize fluoride ions quickly
Step 3: Role of calcium gluconate.
Calcium gluconate provides a source of calcium ionsThese calcium ions bind to free fluoride ions forming insoluble calcium fluorideThis prevents further tissue damage and systemic toxicityHence, calcium gluconate gel is the standard first-line antidote for topical HF exposure
Step 4: Conclusion.
Therefore, the appropriate antidote for hydrofluoric acid exposure is calcium gluconate gel