Question

Which option(s) correctly match(es) the Antibiotic with their corresponding Target?

• A. P - iv; Q - i; R - ii; S - iii
• B. P - ii; Q - iv; R - i; S - iii
• C. P - iv; Q - i; R - ii; T - i
• D. P - iv; Q - i; R - ii; T - i

Hint:

When solving matching questions, carefully review the specific mechanisms of each antibiotic and match them with their respective biological targets.

Answer 1

The Correct Option is A, C

To correctly match the antibiotics with their respective targets, let's look at each antibiotic and its mechanism of action:
- Penicillin (P): Penicillin works by inhibiting the transpeptidase enzyme, which is essential for the synthesis of the bacterial cell wall. Therefore, Penicillin matches with iv (Transpeptidase).
- Kanamycin (Q): Kanamycin is an antibiotic that targets the ribosome to inhibit protein synthesis. This makes Kanamycin match with i (Ribosome).
- Rifampicin (R): Rifampicin targets RNA polymerase, preventing the transcription process in bacteria. As a result, Rifampicin matches with ii (RNA polymerase).
- Nalidixic acid (S): Nalidixic acid targets DNA gyrase, an enzyme involved in DNA replication. It prevents the relaxation of DNA during replication, so Nalidixic acid matches with iii (DNA gyrase).
- Ciprofloxacin (T): Ciprofloxacin is also an inhibitor of DNA gyrase, like Nalidixic acid, and prevents the unwinding of DNA. Therefore, Ciprofloxacin matches with iii (DNA gyrase), not iv.
Thus, the correct options are (A) and (C).