Question

Which one of the following statements about gene expression is INCORRECT?

• A. ( DNA is transcribed to mRNA. )
• B. ( mRNA can be reverse-transcribed to DNA. )
• C. ( mRNA can be translated to protein. )
• D. ( Protein can be reverse-translated to mRNA. )

Hint:

Understanding the central dogma is crucial for grasping how genetic information is processed within biological systems, impacting everything from genetic engineering to disease treatment strategies.

Answer 1

The Correct Option is D

Analyzing the statements about fundamental processes in molecular biology reveals the following: 
(A) Correct: DNA is transcribed to mRNA, a central tenet of molecular biology known as the central dogma. 
(B) Correct: mRNA can indeed be reverse-transcribed to DNA, a process utilized by retroviruses and in techniques such as reverse transcription PCR (RT-PCR). 
(C) Correct: mRNA's translation to protein is a fundamental aspect of gene expression, occurring in the ribosomes of cells. 
(D) Incorrect: Proteins cannot be reverse-translated to mRNA. This statement violates the central dogma of molecular biology, which states that information flows from DNA to RNA to protein, not in reverse from protein. Conclusion:
Explanation: The incorrect statement (D) suggests a reverse flow of genetic information from protein back to mRNA, which is not possible with current biological mechanisms. The central dogma clarifies that once information has passed into protein, it cannot flow back to nucleic acids.