Choose the correct statements:
Statements:
A. In sickle cell anemia, a valine is substituted for the glutamic acid at a location on the surface of the protein near the oxygen-binding site.
B. The red blood cells of people who are homozygous for the sickle cell allele collapse into sickled shape when the oxygen level in the blood is low.
C. Individuals who are heterozygous for the recessive valine-specifying allele are said to possess the sickle cell trait.
Choose the correct answer from the options given below: