Question:

Which of the following statements is incorrect?

Updated On: Nov 13, 2025
  • During aerobic respiration, role of oxygen is limited to the terminal stage.
  • In ETC (Electron Transport Chain), one molecule of $NADH + H^{+}$gives rise to 2 ATP molecules, and one $FADH _{2}$ gives rise to $3$ ATP molecules.
  • ATP is synthesized through complex $V$.
  • Oxidation-reduction reactions produce proton gradient in respiration.
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The Correct Option is B

Solution and Explanation

The question asks to identify the incorrect statement among the given options related to aerobic respiration and the electron transport chain (ETC). Let's evaluate each option:

  1. During aerobic respiration, the role of oxygen is limited to the terminal stage.
    • Oxygen acts as the final electron acceptor in the electron transport chain. It combines with electrons and protons to form water. Therefore, this statement is correct.
  2. In ETC, one molecule of $NADH + H^{+}$ gives rise to 2 ATP molecules, and one $FADH_{2}$ gives rise to $3$ ATP molecules.
    • This statement is incorrect. The actual yield is the reverse: Typically, one molecule of $NADH + H^{+}$ results in approximately 3 ATP molecules, and one molecule of $FADH_{2}$ yields about 2 ATP molecules.
  3. ATP is synthesized through complex $V$.
    • This statement is correct. The synthesis of ATP occurs via ATP synthase, which is indeed part of complex V in the electron transport chain.
  4. Oxidation-reduction reactions produce a proton gradient in respiration.
    • This statement is correct. The transfer of electrons through the ETC is coupled with the translocation of protons across the mitochondrial membrane, creating a proton gradient.

Therefore, the incorrect statement is: "In ETC (Electron Transport Chain), one molecule of $NADH + H^{+}$ gives rise to 2 ATP molecules, and one $FADH_{2}$ gives rise to $3$ ATP molecules."

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Concepts Used:

Electron Transport System

The electron transport chain or system is the sequence of electron carriers, enzymes, and cytochrome that passes electrons from one to another through the redox reaction. It is electron transport-linked phosphorylation.

It contains flavin nucleotides (FAD), nicotinamide adenine dinucleotide (NAD), coenzyme Q, and cytochromes localized in F1 particles of mitochondria. It occurs in the inner mitochondrial membrane along with cristae.

In this process five (5) complexes are involved namely, I- NADH-UQ reductase, II- Succinate-UQ reductase, III- UQH2 -cytochrome C reductase, IV- Cytochrome C oxidase, and V is connected with F0−F1 particles.

In this process, NAD and FAD are minimized.

Steps:

  • Redox at complex I: Four (4) protons are pumped from the matrix to intermembrane space.
  • Redox at complex II: Coenzyme Q collects the electrons from complex I and II, and goes to complex III.
  • Redox of complex III: Four (4) protons are again pumped from matrix to intermembrane space and cytochrome C transports electrons to the complex IV.
  • Redox of complex IV: Two (2) protons are pumped from the matrix to intermembrane space and the formation of water occurs in the matrix.
  • ATP synthase action: It pumps protons from intermembrane space to matrix and generates ATP. It is associated with oxidative phosphorylation.