Question

Which of the following represents the total integrated area under the plasma level time profile and expresses the total amount of drug that comes into systemic circulation after its administration?

• A. C\textsubscript{max}
• B. t\textsubscript{max}
• C. MRT
• D. AUC

Hint:

AUC = total drug absorbed into systemic circulation over time.

Answer 1

The Correct Option is D

AUC (Area Under Curve) represents the total drug exposure over time. It quantifies the extent of drug absorption into systemic circulation and is critical in bioavailability and bioequivalence studies.