Question

Which of the following reactions is suitable for converting an acid amide to an imidazole?

• A. Carbon Emission Reaction
• B. Hofmann Bromide Reaction
• C. Stepan Reaction
• D. Gabriel Thalamide Condensation

Hint:

The Hofmann Bromide reaction is particularly useful for reducing amides to amines by breaking the C-N bond of the carbonyl group.

Answer 1

The Correct Option is B

The Hofmann Bromide reaction is used for the conversion of acid amides to amines with the loss of the carbonyl group. It involves the treatment of an acid amide with bromine (Br$_2$) and a strong base, which leads to the removal of the carbonyl group and the formation of a primary amine. This reaction is suitable for the desired conversion.