Question:

Which of the following is the best method to assess the degree of muscle relaxation?

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Train of Four is widely used in clinical practice to monitor neuromuscular blockade during anesthesia. The number of twitches and the response to the stimulus help gauge the level of muscle relaxation.
Updated On: Apr 30, 2025
  • Tetanic Stimulation
  • Double burst stimulation
  • Train of four
  • Electromyography
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The Correct Option is C

Solution and Explanation

Tetanic Stimulation: This involves the use of a high-frequency stimulus for a prolonged period. While it provides information about the degree of neuromuscular blockade, it is not the most reliable for assessing the degree of muscle relaxation compared to the Train of Four method.
Double burst stimulation: This technique involves two short bursts of stimuli and is more sensitive than tetanic stimulation but still does not offer as comprehensive a view of neuromuscular function as Train of Four.
Train of four: This is the correct answer. The Train of Four (TOF) involves the application of four stimuli at a set interval (typically 2 Hz). The response is measured to determine the degree of neuromuscular blockade. It provides the most reliable and detailed information about the depth of muscle relaxation during anesthesia.
Electromyography: While electromyography can be used to measure electrical activity in muscles, it is more commonly used for diagnosing neuromuscular disorders and is not as commonly employed to assess muscle relaxation during anesthesia. Thus, the correct answer is Train of four (3), as it is the best method for assessing the degree of muscle relaxation during anesthesia.
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