This question asks you to identify which option is not a ribozyme. To determine this, we need to understand what a ribozyme is: a ribozyme is an RNA molecule that can catalyze certain biochemical reactions, similar to proteins which are conventional enzymes.
Let's analyze each option one by one:
- Poly A polymerase: This is an enzyme that adds a poly-A tail to mRNA molecules. It is a protein enzyme, not an RNA molecule, and therefore not a ribozyme.
- Ribonuclease: Ribonucleases are enzymes that degrade RNA, and some forms can be ribozymes.
- Transpeptidase: This term generally refers to enzymes involved in the synthesis of bacterial cell walls. It is not related to RNA and ribozymes.
- Peptidyl Transferase: This is a ribozyme activity of the ribosome. It is responsible for forming peptide bonds between amino acids during protein synthesis.
From this analysis,
Poly A polymerase is the only one that is not a ribozyme.