Step 1: Understanding the Concept:
The endomembrane system is a group of organelles in eukaryotic cells that work together as a functional unit to synthesize, modify, package, and transport proteins and lipids. The question asks to identify the organelle that is not part of this coordinated system.
Step 2: Detailed Explanation:
The components of the endomembrane system include:
\[\begin{array}{rl} \bullet & \text{The nuclear envelope } \\ \bullet & \text{The Endoplasmic reticulum (ER) } \\ \bullet & \text{The Golgi apparatus } \\ \bullet & \text{Lysosomes } \\ \bullet & \text{Vacuoles } \\ \bullet & \text{The plasma membrane } \\ \end{array}\]
These organelles are connected either physically or by the transport of vesicles between them. The Mitochondrion, along with chloroplasts, is not considered part of the endomembrane system. Mitochondria are involved in cellular respiration and have their own distinct membranes and genetic material, believed to have originated through endosymbiosis.
Step 3: Final Answer:
The Mitochondrion is not a component of the endomembrane system.