One of the primary challenges in nanotechnology is maintaining the stability of nanostructures. At the nanoscale, materials exhibit unique properties — such as increased surface area-to-volume ratio and quantum effects — but these also make them highly reactive and susceptible to aggregation, oxidation, and environmental degradation.
Because of their small size and high surface energy, nanoparticles may clump together or change behavior over time, making it difficult to preserve their desired characteristics during storage, processing, or application. This instability can affect performance in fields such as drug delivery, nanoelectronics, or catalysis.
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Therefore, the real challenge lies in maintaining the stability of nanostructures over time and under varying conditions.