Question

Which of the following hyperlipidemic drugs acts by inhibition of PCSK-9?

• A. Atorvastatin
• B. Evolocumab
• C. Ezetimibe
• D. Lomitapide

Hint:

Evolocumab is a PCSK-9 inhibitor used to treat hyperlipidemia, especially in patients with high LDL cholesterol levels who are at risk for cardiovascular events.

Answer 1

The Correct Option is B

The drug that acts by inhibition of PCSK-9 is Evolocumab. PCSK-9 inhibitors are a class of drugs that work by increasing the availability of LDL receptors on liver cells, thus lowering LDL cholesterol levels in the blood. Evolocumab is a monoclonal antibody that inhibits PCSK-9, thereby reducing LDL cholesterol levels.