Question:

Which of the following factors are favourable for the formation of oxyhaemoglobin in alveoli ?

Updated On: May 2, 2025
  • High pO2 and High pCO2
  • High pO2 and Lesser H+ concentration
  • Low pCO2 and High H+ concentration
  • Low pCO2 and High temperature
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The Correct Option is B

Approach Solution - 1

The formation of oxyhaemoglobin in the alveoli is influenced by several factors. To understand which conditions favor this process, we need to consider the following key physiological factors:
  • High partial pressure of oxygen (pO2): Since oxyhaemoglobin formation involves the binding of oxygen to haemoglobin, a higher concentration of oxygen is necessary to drive the reaction forward, favoring the formation of oxyhaemoglobin.
  • Lesser concentration of hydrogen ions (H+): A lower concentration of H+ indicates a higher pH (less acidic), which enhances haemoglobin's affinity for oxygen. This is known as the Bohr effect, where lower acidity improves oxygen binding.
Among the given options, the combination of high pO2 and lesser H+ concentration creates the optimal conditions for forming oxyhaemoglobin in the alveoli by providing sufficient oxygen and a favorable pH for binding.
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Approach Solution -2

Oxyhemoglobin Formation:

  • Oxyhemoglobin forms more readily when oxygen levels are high (high pO₂).
  • It also forms when the concentration of H⁺ ions is lower, as in the lungs, where the pH is relatively higher.

Thus, the correct answer is (2) High pO₂ and Lesser H⁺ concentration.

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