Which of the following does not lead to genetic manipulation of DNA?
Show Hint
- Recombination
- Replication
- Transcription
- Supercoiling
The Correct Option is D
Solution and Explanation
Genetic manipulation refers to processes like recombination, replication, and transcription that change, duplicate, or utilize genetic information.
Step 2: Role of recombination, replication, and transcription.
- Recombination involves exchange of DNA segments, altering genetic material.
- Replication copies DNA, ensuring genetic material is passed on.
- Transcription converts DNA into RNA, a key step in gene expression.
Step 3: Role of supercoiling.
Supercoiling is a structural change that compacts DNA, but it does not directly alter or manipulate the sequence of DNA. It only influences packaging and accessibility.
Step 4: Conclusion.
Thus, supercoiling is not considered a form of genetic manipulation.
Final Answer: \[ \boxed{\text{The correct answer is (D) Supercoiling.}} \]
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