Question

Which of the following clinical feature is not responsible for insulin resistance in type 2 diabetes?

• A. Increased LDL
• B. Increased HDL
• C. Reduced HDL
• D. Increased triglycerides

Answer 1

The Correct Option is B

To determine which clinical feature is not responsible for insulin resistance in type 2 diabetes, we need to evaluate how each option relates to insulin resistance:

1. Increased LDL (Low-Density Lipoprotein):
   Increased levels of LDL are often associated with cardiovascular risks. While elevated LDL does not directly cause insulin resistance, it is part of a cluster of metabolic disturbances (dyslipidemia) associated with type 2 diabetes.
2. Increased HDL (High-Density Lipoprotein):
   HDL is known as the "good" cholesterol. Higher levels of HDL are generally protective against cardiovascular diseases and are inversely related to the risk factors of metabolic syndrome. Increased HDL is typically beneficial and not associated with insulin resistance.
3. Reduced HDL:
   Low levels of HDL cholesterol are commonly seen in individuals with insulin resistance and metabolic syndrome. Hence, reduced HDL can contribute to insulin resistance.
4. Increased triglycerides:
   High triglyceride levels are often seen in people with insulin resistance and are considered part of the lipid profile alteration in type 2 diabetes.

Based on this analysis, increased HDL is the feature that does not contribute to insulin resistance in type 2 diabetes. Increased HDL has a protective role and is not considered a risk factor for insulin resistance.