Return on Investment (ROI) is a profitability ratio as it measures how efficiently a company generates profits from its investments. - Price Earning Ratio (P/E Ratio) is related to profitability because it shows the relationship between the company’s earnings and its share price. - Earnings per Share (EPS) is a key indicator of profitability as it represents the portion of a company’s profit allocated to each outstanding share. - Debt Equity Ratio, however, is a solvency ratio, not a profitability ratio.