Question

Which fungus is most commonly associated with orbital cellulitis in patients with diabetic ketoacidosis.

• A. Candida
• B. Mucor
• C. Aspergillus
• D. Rhizopus

Answer 1

The Correct Option is C

The fungus most commonly associated with orbital cellulitis in patients with diabetic ketoacidosis is Rhizopus. This is part of a group of fungi known as Mucorales, which are responsible for mucormycosis, a severe infection seen in immunocompromised individuals, particularly those with diabetes mellitus and acidosis. Despite Aspergillus being initially mentioned as the correct answer, it's important to note that mucormycosis is specifically linked to diabetic ketoacidosis scenarios more frequently than Aspergillus. In summary:

• Mucor and Rhizopus are primary agents in mucormycosis.
• These fungi invade tissues using their hyphae and can lead to angioinvasion, tissue necrosis, and characteristic black eschar formation.
• Effective management involves antifungal therapy and often surgical debridement.