Question

Which drug acts via the tyrosine kinase receptor?

• A. Insulin
• B. TSH
• C. LH
• D. MSH

Answer 1

The Correct Option is A

To determine which drug acts via the tyrosine kinase receptor, we must first understand the mechanism of action for each option:

• Insulin: Insulin operates through the tyrosine kinase receptor, which is a cell surface receptor that, upon insulin binding, undergoes autophosphorylation on tyrosine residues, leading to a cascade of intracellular signaling events.
• TSH (Thyroid Stimulating Hormone): TSH acts through a G protein-coupled receptor, which is quite different from a tyrosine kinase receptor.
• LH (Luteinizing Hormone): LH also utilizes a G protein-coupled receptor to exert its effects, similar to TSH.
• MSH (Melanocyte-Stimulating Hormone): MSH interacts with a G protein-coupled receptor, not a tyrosine kinase receptor.

From the analysis above, the only drug that engages with the tyrosine kinase receptor is Insulin.