Question:

Which best explains “Flipping effect”?

Updated On: Jul 12, 2025
  • LDH 1 > LDH 2
  • LDH2 > LDH1
  • LDH 2 > LDH 3
  • LDH 3 > LDH 2
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The Correct Option is A

Solution and Explanation

The "Flipping effect" refers to a situation in clinical diagnostics where the levels of lactate dehydrogenase (LDH) isoenzymes in the blood show a reversal of the normal pattern. Normally, LDH-2 is greater than LDH-1; however, in some pathological conditions such as myocardial infarction, this pattern is reversed, resulting in LDH-1 being greater than LDH-2, which is termed the "Flipping effect." Therefore, the correct explanation of the "Flipping effect" is represented by the ratio LDH 1 > LDH 2.
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