Question

Which among the following is most probable reason for preference of Cisatracurium over atracurium?

• A. Decreased histamine release
• B. Increased histamine release
• C. Due to elimination by Hofmann elimination
• D. Increased CNS toxicity

Answer 1

The Correct Option is A

The preference for Cisatracurium over atracurium primarily stems from its decreased histamine release. Histamine release is a significant concern with certain muscle relaxants, as it can lead to adverse effects such as hypotension and bronchospasm. Atracurium is known to cause more histamine release compared to Cisatracurium. Therefore, in clinical settings where minimizing such side effects is crucial, Cisatracurium is preferred due to its lower propensity to release histamine, enhancing its safety profile.