The number of 6-letter words, with or without meaning, that can be formed using the letters of the word MATHS such that any letter that appears in the word must appear at least twice, is $ 4 \_\_\_\_\_$.
Permutation is the method or the act of arranging members of a set into an order or a sequence.
Combination is the method of forming subsets by selecting data from a larger set in a way that the selection order does not matter.