Question

What is the role of RNA polymerase III in the process of transcription in Eukaryotes?

• A. Transcription of tRNA, 5 srRNA and snRNA
• B. Transcription of precursor of mRNA
• C. Transcription of only snRNAs
• D. Transcription of rRNAs (28S, 18S and 5.88)

Answer 1

The Correct Option is A

In eukaryotic cells, transcription is carried out by three different RNA polymerases, each responsible for synthesizing distinct types of RNA. The role of RNA polymerase III is to transcribe small RNA molecules, including transfer RNA (tRNA), 5S ribosomal RNA (5S rRNA), and certain small nuclear RNAs (snRNA).

1. tRNA Transcription: RNA polymerase III synthesizes tRNAs which play a crucial role in protein synthesis by translating mRNA sequences into amino acids, forming polypeptides.

2. 5S rRNA Transcription: This polymerase also transcribes 5S rRNA, a component of the large subunit of the ribosome. It assists in ribosomal assembly and function during protein synthesis.

3. snRNA Transcription: Some snRNAs, which are involved in RNA splicing and other regulatory processes, are transcribed by RNA polymerase III.

RNA Type	Role
tRNA	Translates mRNA into amino acids
5S rRNA	Part of the ribosome's large subunit
snRNA	Involved in RNA processing and regulation

The correct role of RNA polymerase III is to transcribe tRNA, 5S rRNA, and snRNA.

Answer 2

RNA polymerase III is responsible for transcribing small functional RNAs, including transfer RNAs (tRNAs), 5S ribosomal RNA (rRNA), and some small nuclear RNAs (snRNAs). It does not transcribe mRNA precursors or the large rRNA subunits (28S, 18S, and 5.8S) as mentioned in option (D).

Therefore, The correct option is (A): Transcription of tRNA, 5 srRNA and snRNA