Question

What is mechanism of action of Curanium drugs as muscle relaxant ?

• A. Persistently depolarizing at Neuromuscular junction
• B. Act competitively on Ach receptors blocking post-synaptically
• C. Repetitive stimulation of Ach receptors on muscle end plate
• D. Inhibiting the calcium channel on presynaptic membrane

Answer 1

The Correct Option is B

Curanium drugs, used as muscle relaxants, primarily function by acting competitively on acetylcholine (Ach) receptors. This action occurs at the neuromuscular junction, specifically targeting post-synaptic receptors. When these drugs bind to the Ach receptors, they prevent acetylcholine, a neurotransmitter, from attaching to its site. This competitive inhibition blocks neuromuscular transmission, ultimately leading to muscle relaxation. By obstructing acetylcholine's action, Curanium drugs effectively reduce muscle contractions and are utilized in various medical procedures requiring muscle relaxation. Understanding this mechanism highlights their role in competitive inhibition at the receptor level.