Question

What are the therapy options in this patient?

Hint:

The treatment of choice for Factor XIII deficiency is FXIII concentrate, which provides a more reliable and targeted therapy than FFP.

Answer 1

Step 1: Therapy for Factor XIII Deficiency.
Management of Factor XIII deficiency aims to prevent bleeding episodes and manage active bleeding. Therapy options include: 1. Factor XIII concentrate: The primary treatment for FXIII deficiency is the intravenous administration of Factor XIII concentrate. This helps to replace the deficient factor and stabilize the fibrin clot.
2. Fresh frozen plasma (FFP): In emergencies, FFP can be used as a temporary measure to provide FXIII, though it is not as effective as the concentrate.
3. Supportive care: Patients with mild deficiency may require treatment only during periods of increased bleeding risk, such as surgery or trauma. Routine monitoring of FXIII levels is essential to guide therapy.