Question

What are the long-term side effects associated with chronic isoniazid use?

• A. Cardiotoxicity
• B. Hepatotoxicity, peripheral neuropathy
• C. Loss of hair
• D. Immunotoxicity

Hint:

Isoniazid → supplement with B6 to prevent peripheral neuropathy.

Answer 1

The Correct Option is B

Isoniazid, used in tuberculosis treatment, may cause hepatotoxicity and peripheral neuropathy with long-term use. Pyridoxine (vitamin B6) is co-administered to prevent neuropathy.