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What are the different modalities of ECMO (Extra-Corporeal Membrane Oxygenation) used in critically ill patients?

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ECMO is a critical life-saving procedure, and the choice of modality is based on whether the patient requires respiratory support alone or both cardiac and respiratory support.
Updated On: Dec 12, 2025
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Solution and Explanation


Step 1: Understanding ECMO.
ECMO is a life-support technique used in critically ill patients who are experiencing severe cardiac or respiratory failure. It provides temporary support by oxygenating the blood and removing carbon dioxide when the patient's lungs or heart are unable to do so effectively. ECMO involves circulating the patient's blood through an artificial lung (oxygenator) and returning it to the body.

Step 2: Different modalities of ECMO.
1. Veno-venous ECMO (VV ECMO): This modality is used for patients with severe respiratory failure. It involves drawing blood from a vein, oxygenating it outside the body, and returning it to a vein. VV ECMO supports the lungs by providing oxygenation and carbon dioxide removal. It does not provide support for the heart.
2. Veno-arterial ECMO (VA ECMO): This modality is used for patients with both cardiac and respiratory failure. Blood is drawn from a vein, oxygenated outside the body, and then returned to the arterial system, which supports both the heart and lungs. VA ECMO provides both cardiac and respiratory support.
3. Artero-venous ECMO (AV ECMO): A less common modality, AV ECMO is typically used for patients with severe metabolic acidosis. Blood is oxygenated via an arterial-venous loop system.

Step 3: Conclusion.
The choice of ECMO modality depends on the type of organ failure (cardiac vs respiratory) and the patient’s clinical condition. VV ECMO is primarily used for respiratory failure, while VA ECMO is used when both cardiac and respiratory support is needed.
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