Question

Vitamin A is stored in:

• A. Cells of Ito
• B. Hepatocyte
• C. Endothelial cell
• D. Kupffer cell

Answer 1

The Correct Option is A

Vitamin A is predominantly stored in the liver, specifically within the special cells known as Cells of Ito. These cells are located in the liver's perisinusoidal space, which is part of the hepatic tissue structure.

To further understand:

• Cells of Ito: These are also called stellate cells or hepatic stellate cells. They are known for storing vitamin A in the form of retinyl esters within lipid droplets. Under certain conditions, they can transform into myofibroblasts responsible for liver fibrosis.
• Hepatocyte: These are the main functional cells of the liver but do not primarily store vitamin A. Instead, they perform various metabolic, detoxifying, and protein-synthesis functions.
• Endothelial cell: These cells line blood vessels and have roles in filtration and barrier functions but are not involved in vitamin A storage.
• Kupffer cell: These are liver macrophages involved in immune response and clearing pathogens, but they do not store vitamin A.

In summary, among the given options, the Cells of Ito are specifically responsible for vitamin A storage in the liver.