Question:

Van Nuys prognostic index is not based on:

Updated On: Jul 12, 2025
  • Age
  • Microcalcification
  • Size
  • ER status
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The Correct Option is D

Solution and Explanation

The Van Nuys Prognostic Index (VNPI) is a tool used to assess the prognosis of patients with ductal carcinoma in situ (DCIS) of the breast. It involves several factors to evaluate the potential aggressiveness and likelihood of recurrence of cancer. The main components typically used in the VNPI are:
  • Age: Older age may be associated with different risk profiles.
  • Size of Tumor: Larger tumors usually indicate a higher risk of recurrence.
  • Microcalcification: The presence and type of calcifications can suggest tumor characteristics.
It is important to note that while estrogen receptor (ER) status is a significant factor in many breast cancer evaluations, it is not a parameter included in the calculation of the Van Nuys Prognostic Index. Therefore, the correct answer is:
  • ER Status
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