Question:

Urease enzyme catalyzes the conversion of urea into ammonia and carbon dioxide. Which one of the following organisms expresses urease enzyme?

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The presence of urease is a diagnostic marker for Helicobacter pylori infection, often detected through breath tests in clinical settings.
Updated On: Feb 1, 2025
  • ( Caenorhabditis elegans )
  • ( Drosophila melanogaster )
  • ( Helicobacter pylori )
  • ( Homo sapiens )
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The Correct Option is C

Solution and Explanation

The urease enzyme is crucial for certain bacteria to survive in acidic environments by catalyzing the conversion of urea into ammonia, which can neutralize acid. Analysis of Each Option: (A) Incorrect: Caenorhabditis elegans, a nematode, does not utilize urease as part of its metabolic processes. (B) Incorrect: Drosophila melanogaster, commonly known as the fruit fly, does not produce urease. (C) Correct: Helicobacter pylori expresses urease, which is a critical factor in its ability to colonize the human stomach, neutralizing stomach acid through the production of ammonia. (D) Incorrect: Humans (Homo sapiens) do not produce urease. The presence of urease in humans is typically associated with bacterial infection. Conclusion:
Explanation: Helicobacter pylori's expression of urease is a well-documented mechanism that helps protect the bacteria from the acidic environment of the stomach, enabling it to cause infections that can lead to ulcers and other gastrointestinal disorders.
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