Question

“Transforming Principle” was given by:

• A. Maclyn McCarty
• B. Frederick Griffith
• C. Alfred Hershey
• D. Watson and Crick

Answer 1

The Correct Option is B

Frederick Griffith discovered the 'Transforming Principle' in 1928 through his experiments with Streptococcus pneumoniae. He observed that non-virulent strains could be transformed into virulent strains when exposed to heat-killed virulent cells, indicating the presence of a transferable genetic material.

Answer 2

The "Transforming Principle" was first identified by Frederick Griffith in 1928 during his experiment with Streptococcus pneumoniae bacteria. Griffith discovered that non-virulent (harmless) bacteria could be transformed into virulent (disease-causing) bacteria when exposed to heat-killed virulent bacteria. This transformation was later found to be caused by the transfer of genetic material, which was referred to as the "transforming principle."

• Maclyn McCarty, working later in 1944, identified that the transforming principle was DNA.
• Alfred Hershey and Martha Chase later confirmed that DNA was the genetic material in their famous experiment with bacteriophages.
• Watson and Crick are credited with discovering the structure of DNA, but they did not give the "transforming principle."