Question

Therapeutic drug monitoring is advised in all except

• A. Tacrolimus
• B. Cyclosporine
• C. Metformin
• D. Phenytoin

Hint:

Metformin does not require TDM due to its low toxicity risk at therapeutic doses.

Answer 1

The Correct Option is C

Therapeutic drug monitoring (TDM) is not routinely required for metformin as it has a wide therapeutic index and predictable pharmacokinetics. In contrast, drugs like tacrolimus, cyclosporine, and phenytoin have narrow therapeutic windows and require regular monitoring.