Question

The rate limiting step for the absorption of controlled release tablet is the:

• A. Metabolism of the drug
• B. Excretion of the drug
• C. Dissolution of the drug
• D. Distribution of the drug

Hint:

In controlled release formulations, the dissolution of the drug is often the slowest step, determining the overall release and absorption rate.

Answer 1

The Correct Option is C

For controlled release tablets, the rate limiting step for absorption is typically the dissolution of the drug. This is because the drug needs to dissolve in the gastrointestinal tract before it can be absorbed into the bloodstream. The controlled release mechanism is designed to slow down the dissolution rate for prolonged therapeutic effect.