Question:

Core tablet coated with cellulose acetate phthalate has been administered to a patient. Where do you expect the drug to be released:

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Cellulose acetate phthalate (CAP) coatings are commonly used for enteric coatings, ensuring drug release in the intestine where the pH is more favorable for the dissolution of the coating.
Updated On: Feb 4, 2025
  • Liver
  • Intestine
  • Oral cavity
  • Stomach
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The Correct Option is B

Solution and Explanation

Cellulose acetate phthalate (CAP) is a pH-sensitive coating that is designed to dissolve in the intestine, which has a higher pH compared to the stomach. This allows the drug to be released in the intestine, avoiding degradation in the acidic environment of the stomach.

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