Question

Core tablet coated with cellulose acetate phthalate has been administered to a patient. Where do you expect the drug to be released:

• A. Liver
• B. Intestine
• C. Oral cavity
• D. Stomach

Hint:

Cellulose acetate phthalate (CAP) coatings are commonly used for enteric coatings, ensuring drug release in the intestine where the pH is more favorable for the dissolution of the coating.

Answer 1

The Correct Option is B

Cellulose acetate phthalate (CAP) is a pH-sensitive coating that is designed to dissolve in the intestine, which has a higher pH compared to the stomach. This allows the drug to be released in the intestine, avoiding degradation in the acidic environment of the stomach.