The primary structure of the enzyme Lysozyme was discovered first. Lysozyme, an enzyme found in tears, saliva, and other body fluids, was the first enzyme whose structure was solved in detail. The work was carried out by the scientists Sir Alexander Fleming and later by others, providing significant insight into enzyme function and structure. This discovery paved the way for further studies into the structures of other enzymes, such as Rnase A, Trypsin, and Carboxypeptidase.