Question:

The number of hydrogen bonds between adenine and thymine is _____.

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{A--T = 2 bonds, G--C = 3 bonds} Remember: AT is weaker than GC due to fewer hydrogen bonds.
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Solution and Explanation

Concept: DNA consists of two polynucleotide strands held together by hydrogen bonds between complementary nitrogenous bases. The pairing follows Chargaff’s base pairing rule:
  • Adenine (A) pairs with Thymine (T)
  • Guanine (G) pairs with Cytosine (C)
Each base pair is stabilized by a specific number of hydrogen bonds, which contribute to the stability of the DNA double helix.
Explanation: Adenine and thymine form two hydrogen bonds between them. In contrast, guanine and cytosine form three hydrogen bonds, making the G--C pair more stable than the A--T pair. Thus, the number of hydrogen bonds between adenine and thymine is 2.
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