Question:

The enzyme Recombinase is required at which stage of Meiosis I?

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Crossing over during meiosis increases genetic diversity in sexually reproducing organisms.

Updated On: Apr 8, 2025
  • Pachytene
  • Zygotene
  • Diplotene
  • Diakinesis
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The Correct Option is A

Approach Solution - 1

The enzyme Recombinase is required at Pachytene stage of Meiosis I.

(A) Pachytene - Correct: Recombinase (including RAD51 and DMC1) mediates crossing over during pachytene.

(B) Zygotene - Incorrect: Synapsis occurs here, but recombination happens later.

(C) Diplotene - Incorrect: Chiasmata become visible here, but recombination is complete.

(D) Diakinesis - Incorrect: This is the stage of terminalization of chiasmata.

The correct answer is (A) Pachytene, when homologous recombination occurs via recombinase enzymes.

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Approach Solution -2

Recombinase is involved in the process of genetic recombination during meiosis. This process occurs during the pachytene stage of Meiosis I when homologous chromosomes exchange segments of genetic material. Recombination is crucial for generating genetic diversity.

Other stages:

  • Zygotene is when homologous chromosomes begin to pair, but recombination does not occur.
  • Diplotene and Diakinesis involve other aspects of chromosome behavior, but recombination is completed during pachytene.

Option (A) is correct as recombinase is active during the pachytene stage.

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