Question

The drug of choice for absence seizures is:

• A. Phenytoin
• B. Carbamazepine
• C. Ethosuximide
• D. Valproic acid

Hint:

Absence seizures: “Ethosuximide — it Sux to have Silent Seizures.”

Answer 1

The Correct Option is C

Ethosuximide is the first-line drug for absence seizures. It works by blocking T-type calcium channels in thalamic neurons, preventing the abnormal rhythmic firing that causes absence seizures.
- Valproic acid is used if ethosuximide is ineffective or if there are mixed seizure types.
- Phenytoin and carbamazepine are not effective for absence seizures and may worsen them.