Question

The diversity in T-cell receptors is generated by:

• A. Gene rearrangements
• B. Somatic hypermutation of rearranged V region
• C. Gene conversion
• D. Class switching

Hint:

T-cell receptor diversity is generated through genetic recombination, allowing the immune system to recognize a wide range of pathogens.

Answer 1

The Correct Option is A

T-cell receptor diversity is primarily generated by genetic mechanisms that create variability in the receptor molecules.
Gene Rearrangements
T-cell receptor diversity is mainly generated by gene rearrangements, a process that involves the recombination of variable (V), diversity (D), and joining (J) gene segments. This is a key mechanism in generating a diverse repertoire of T-cell receptors.
Thus, the correct answer is \( \boxed{A} \).