Question:

The cofactor of the enzyme carboxypeptidase is :

Updated On: Mar 27, 2025
  • Zinc
  • Niacin
  • Flavin
  • Haem
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The Correct Option is A

Solution and Explanation

The cofactor of the enzyme carboxypeptidase is:

Option 1: Zinc

Explanation:

Carboxypeptidase is a protease enzyme that hydrolyzes peptide bonds at the C-terminal end of proteins. It requires a metal ion cofactor for its activity, and that cofactor is zinc (Zn2+). The zinc ion is essential for the catalytic mechanism of carboxypeptidase.

Let's look at why the other options are incorrect:

  • Niacin: Niacin is a component of NAD and NADP, which are coenzymes involved in redox reactions.
  • Flavin: Flavin (FAD or FMN) is a cofactor involved in redox reactions, often in enzymes like dehydrogenases and oxidases.
  • Haem: Haem is a cofactor found in proteins like hemoglobin and cytochromes, involved in oxygen transport and electron transfer.
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