The assembly consists of four point masses, each of mass $m$, located at a distance $c$ from the central point $O$ along horizontal and vertical rods. Since the rods are massless, the moment of inertia of the system about $O$ is:
\[
I = m c^2 + m c^2 + m c^2 + m c^2 = 4mc^2
\]
The external force acting is $2F$ applied horizontally at the top mass. This force produces a torque about point $O$. The moment arm is the perpendicular distance $c$, so the torque is:
\[
\tau = (2F)(c) = 2Fc
\]
Using rotational dynamics, the angular acceleration is:
\[
\alpha = \frac{\tau}{I}
= \frac{2Fc}{4mc^2}
= \frac{F}{2mc}
\]
Thus, the angular acceleration of the assembly is:
\[
\alpha = \frac{F}{2mc}
\]