Question:

Thalassemia and sickle cell anemia are caused due to a problem in globin molecule synthesis. Select the correct statement :

Updated On: Jul 20, 2024
  • Both are due to a quantitative defect in globin chain synthesis
  • Thalassemia is due to less synthesis of globin molecules
  • Sickel cell anemia is due to a quantitative problem of globin molecules
  • Both are due to a qualitive defect in globin chain synthesis
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The Correct Option is B

Solution and Explanation

Thalassemia differs from sickle-cell anaemia in that
the former is a quantitative problem of synthesising too few globin molecules while the latter is a qualitative problem of synthesising an incorrectly functioning globin.
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Concepts Used:

Mendelian Disorders

Mendelian Disorder is a type of genetic disorder that is caused due to alterations in one gene or abnormalities in the genome. These disorders can be seen since birth and can be deduced using the Pedigree Analysis.