Question:

Suppose DNA samples collected for DNA fingerprinting analysis are less than the required quantity. Which of the following techniques is helpful to make the samples sufficient for above analysis?

Updated On: Apr 9, 2025
  • Electrophoresis
  • Chromatography
  • PCR
  • DNA probing
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The Correct Option is C

Approach Solution - 1

PCR (Polymerase Chain Reaction) is a technique used to amplify (make millions of copies of) a small amount of DNA, making it sufficient for analysis like DNA fingerprinting.

  • (A) Electrophoresis: Separates DNA fragments by size but does not amplify DNA.
  • (B) Chromatography: Separates molecules based on chemical properties but cannot replicate DNA.
  • (D) DNA probing: Identifies specific DNA sequences using labeled probes but does not increase DNA quantity.

Thus, PCR (C) is the only technique that solves the problem of insufficient DNA samples.

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Approach Solution -2

PCR (Polymerase Chain Reaction): Amplifies tiny DNA samples exponentially.

Other techniques:

  • (A) Electrophoresis: Separates DNA by size.
  • (B) Chromatography: Separates molecules by affinity.
  • (D) DNA probing: Detects specific sequences.

The correct answer is (C) PCR.

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