Question

Sumatriptan is selective ……… agonist.

• A. 5HT\textsubscript{3}
• B. 5HT\textsubscript{4}
• C. 5HT\textsubscript{1B/1D}
• D. 5HT\textsubscript{2A}

Hint:

Sumatriptan = 5HT\textsubscript{1B/1D} agonist → treats migraines.

Answer 1

The Correct Option is C

Sumatriptan is a selective agonist at 5HT\textsubscript{1B/1D} receptors, used primarily in the treatment of acute migraine attacks. Activation of these receptors leads to vasoconstriction of cranial blood vessels and inhibition of pro-inflammatory neuropeptide release.