Question

Solitary lytic lesions seen in

• A. Atherosclerosis
• B. Multiple myeloma
• C. Mitral stenosis
• D. Osteoblast

Answer 1

The Correct Option is B

Solitary lytic lesions are typically associated with diseases that involve bone resorption or destruction. In the given options, these lesions are most commonly linked to Multiple Myeloma, a type of cancer that originates in the plasma cells of bone marrow. This condition leads to the formation of multiple lytic bone lesions due to increased osteoclast activity.

Let's analyze the other options:

• Atherosclerosis: This is a condition involving the hardening and narrowing of the arteries due to plaque buildup. It does not cause lytic bone lesions.
• Mitral stenosis: A heart valve disorder that does not involve bone lesions but affects the mitral valve's ability to open properly.
• Osteoblast: These are bone-forming cells. While they are important in bone formation and repair, they are not related to causing lytic lesions. In fact, increased osteoblastic activity could have the opposite effect, leading to bone formation rather than lysis.

Therefore, the correct answer is Multiple myeloma, which is characterized by the presence of solitary or multiple lytic bone lesions due to the pathological activity of malignant plasma cells.